while (1)
{

HAL_GPIO_TogglePin(GPIOC, 1 << 13);

}

  while (1)
{

      GPIOC->ODR ^= 1 << 13;
}

while(1)
{
  GPIOC->BSRR = (1 << 13) << 0;
  GPIOC->BSRR = (1 << 13) << 16;
}

while(1)
{
  GPIOC->BSRR = (1 << 13);
  GPIOC->BRR = (1 << 13);
}

static __inline volatile uint32_t* bb_bit_address(volatile uint32_t* p, uint_fast8_t bit)
{
    return (
        (volatile uint32_t*) (
            (((uint32_t)p & 0xf0000000UL) | 0x02000000UL)
          + ((((uint32_t)p & 0x000fffffUL)<<5) | (bit<<2))
        )
    );
}

#define _PIN_BITBAND_RD_PTR(XPORT, XPIN, ...)    bb_bit_address(&GPIO##XPORT->IDR, XPIN)
#define _PIN_BITBAND_WR_PTR(XPORT, XPIN, ...)    bb_bit_address(&GPIO##XPORT->ODR, XPIN)

#define _PIN_TOGGLE(XPORT, XPIN, ...)  do {*_PIN_BITBAND_WR_PTR(XPORT, XPIN) = ~*_PIN_BITBAND_RD_PTR(XPORT, XPIN);} while (0)
#define pin_toggle(PIN)            _PIN_TOGGLE(PIN)

#define PIN_LED_RED           B,9,H,OUTPUT_PUSH_PULL,SPEED_10MHZ // можно и 50MHZ, но не особо нужно...

pin_init(PIN_LED_RED);

for(;;)
   pin_toggle(PIN_LED_RED);

  while (1)
{
        GPIOC->BSRRH = (1 << 13);
      GPIOC->BSRRL = (1 << 13);
}

8000bb2:    6823          ldr    r3, [r4, #0]
8000bb4:    ea6f 0203     mvn.w    r2, r3
8000bb8:    602a          str    r2, [r5, #0]
8000bba:    e7fa          b.n    8000bb2 <Reset_Handler+0xc2>

for (;;)
{
    pin_set(PIN_LED_RED);
    pin_clr(PIN_LED_RED);
}

8000bae:    6123          str    r3, [r4, #16]
8000bb0:    6163          str    r3, [r4, #20]
8000bb2:    e7fc          b.n    8000bae <Reset_Handler+0xbe>